Liver Cancer Rates Increasing in North America, Study Says

Increased incidence rates may be partly due to increased chronic HCV infection as a result of unscreened blood transfusions and contaminated needles used for medical purposes, and with widespread intravenous drug use in previous decades.

A new study finds liver cancer incidence rates continue to increase in some low-risk parts of the world such as North America, and are decreasing in some of the highest risk countries in Asia. Despite this, the incidence rates in Asian countries remain twice as high as those in Africa and more than four times as high as rates in North America. The study will be published in an upcoming issue of Cancer Epidemiology Biomarkers and Prevention.

Using data from the International Agency for Research on Cancer, American Cancer Society epidemiologists Melissa M. Center, MPH, and Ahmedin Jemal, Ph.D., examined recent trends in liver cancer incidence rates from 1993 to 2002 for 32 cancer registries worldwide. They also examined the male-to-female rate ratios for these and four additional registries, based on the 1998-2002 incidence data.

They found liver cancer incidence rates for both men and women increased from 1993 to 2002 for eight of the 32 cancer registries considered in the analysis. Increases were largely confined to economically developed countries of Western Europe, North America, and Oceania and may be partly due to increased chronic HCV infection as a result of unscreened blood transfusions and contaminated needles used for medical purposes and with widespread intravenous drug use in previous decades.

In contrast, rates decreased in both men and women in five registries, including three in Asia. Despite this, incidence rates in Asian countries remain three to four times higher than those in low-risk areas with increasing rates. Male-to-female rate ratios varied from 0.9 in sub-Saharan African and South American registries to 5.0 (five men for every one woman diagnosed) in France and Egypt.

The authors concluded that liver cancer incidence rates continue to increase in some low-risk parts of the world, while they are now decreasing in some of the highest risk countries in Asia. Additional studies looking at causation are needed, they say, to further elucidate factors contributing to these divergent liver cancer incidence trends worldwide.

“We hope our description of international liver cancer incidence trends may stimulate studies to further illustrate etiologic factors associated with these divergent liver cancer incidence trends worldwide,” Center said.

Download Center

HTML - No Current Item Deck
  • Free Safety Management Software Demo

    IndustrySafe Safety Management Software helps organizations to improve safety by providing a comprehensive toolset of software modules to help businesses identify trouble spots; reduce claims, lost days, OSHA fines; and more.

  • Get the Ultimate Guide to OSHA Recordkeeping

    When it comes to OSHA recordkeeping there are always questions regarding the requirements and in and outs. IndustrySafe is here to help. We put together this page with critical information to help answer your key questions about OSHA recordkeeping.

  • Safety Training 101

    When it comes to safety training, no matter the industry, there are always questions regarding requirements and certifications. We put together a guide that’s easy to digest so you can ensure you're complying with OSHA's training standards.

  • Conduct EHS Inspections and Audits

    Record and manage your organization’s inspection data with IndustrySafe’s Inspections module. IndustrySafe’s pre-built forms and checklists may be used as is, or can be customized to better suit the needs of your organization.

  • Track Key Safety Performance Indicators

    IndustrySafe’s Dashboard Module allows organizations to easily track safety KPIs and metrics. Gain increased visibility into your business’ operations and safety data.

  • Industry Safe
comments powered by Disqus