Study: Depression Has Big Impact on Stroke, TIA Survivors

Nearly 70 percent of stroke and TIA patients with persistent depression still weren’t treated with antidepressant therapy at either the 3 or 12 month intervals.

Depression is more prevalent among stroke and transient ischemic attack survivors than in the general population, researchers reported in the American Heart Association’s journal Stroke.

While most patients with stroke in the study had only mild disability, and only a fraction of those with TIAs had severe disability, depression rates were similar.

“The similar rates of depression following stroke and TIA could be due to similarities in the rates of other medical conditions or to the direct effects of brain injury on the risk of depression, but more studies are needed,” said Nada El Husseini, M.D., M.H.S., an author of the study and a Stroke Fellow in the Department of Medicine, Division of Neurology, at Duke University Medical Center in Durham, N.C.

Researchers, analyzing 1,450 adults with ischemic stroke (blockage of a blood vessel in the brain) and 397 with TIA, found:

Three months after hospitalization, depression affected 17.9 percent of stroke patients and 14.4 percent of TIA patients.

At 12 months, depression affected 16.4 percent of stroke patients and 12.8 percent of TIA patients.

Nearly 70 percent of stroke and TIA patients with persistent depression still weren’t treated with antidepressant therapy at either the 3 or 12 month intervals.

“Patients need to be open about their symptoms of depression and discuss them with their physicians so that they can work together to improve outcomes,” El Husseini said. “It is important for physicians to screen for depression on follow-up after both stroke and TIA.”

Researchers defined depression using the Patient Health Questionnaire-8 (PHQ-8), which covers a range of depressive symptoms: loss of interest and pleasure in doing things; feelings of sadness, helplessness, and hopelessness; insomnia or oversleeping; lack of energy; feelings of worthlessness; inability to concentrate; loss of appetite or overeating; and moving or speaking slowly. Patients who scored 10 or more on that questionnaire were considered depressed.

Patients with stroke, who had persistent depression, tended to be younger, have greater stroke-related disability, and couldn’t work at three months follow-up.

“Physicians may need to be more vigilant in screening these patients because of their higher risk for long-term and persistent depression,” El Husseini said.

The study participants were in the AVAIL (Adherence eValuation After Ischemic Stroke Longitudinal) Study and patients in hospitals participating in the American Heart Association’s Get With The Guidelines™-Stroke in 2006-08.

The median age was 64 for stroke patients and 68 for TIA patients. About 44 percent of the stroke patients and 54 percent of the TIA patients were women. The majority of patients were white. AVAIL included a geographically national representative group of 106 hospitals.

Download Center

HTML - No Current Item Deck
  • Safety Management Software - Free Demo

    IndustrySafe Safety Software’s comprehensive suite of modules help organizations to record and manage incidents, inspections, hazards, behavior based safety observations, and much more. Improve safety with an easy to use tool for tracking, notifying and reporting on key safety data.

  • The Top 5 Safety and Technology Trends to Watch in 2020

    Get the latest on trends you can expect to hear more about in 2020, including continued growth of mobile safety applications, wearable technology, and smart PPE; autonomous vehicles; and increased adoption of international safety standard, ISO 45001.

  • Get the Ultimate Guide to OSHA Recordkeeping

    OSHA’s Form 300A posting deadline is February 1! Are you prepared? To help answer your key recordkeeping questions, IndustrySafe put together this guide with critical compliance information.

  • The 4 Stages of an Incident Investigation

    So, your workplace has just experienced an incident resulting in the injury or illness of a worker. Now what? OSHA recommends that you conduct investigations of workplace incidents using a four-step system.

  • Why Is Near Miss Reporting Important?

    A near miss is an accident that's waiting to happen. Learn how to investigate these close calls and prevent more serious incidents from occurring in the future.

  • Industry Safe
comments powered by Disqus

OH&S Digital Edition

  • OHS Magazine Digital Edition - November December 2019

    November / December 2019

    Featuring:

    • GAS DETECTION
      Redefining Compliance for the Gas Detection Buyer
    • FALL PROTECTION
      Don't Trip Over the Basics
    • VISION PROTECTION
      What to Look for in Head-to-Toe PPE Solutions
    • PROTECTIVE APPAREL
      Effective PPE for Flammable Dust
    View This Issue