Northwestern Researchers' Method May Tame Resistant Bacteria

Two researchers from Northwestern University's Department of Biochemistry, Molecular Biology and Cell Biology, Luciano A. Marraffini and Erik J. Sontheimer, report in a paper today in the journal Science that a method has been found to "counteract multiple routes of [horizontal gene transfer] and can limit the spread of antibiotic resistance in pathogenic bacteria." The method may be a solution to bacteria such as Methicillin-resistant Staphylococcus aureus (MRSA), which causes about 100,000 serious infections in the United States each year, according to the Centers for Disease Control and Prevention.

Their paper, "CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA," is available via this site and already has been hailed in a brief article posted yesterday by the Chicago Tribune.

In that article, written by reporter Robert Mitchum, Sontheimer said any clinical application of the method is years away, and he "does not know whether the process would be able to fight an acute infection." But the process could prevent bacteria from developing new resistance, he said.

"We'll never have the killer drug that just ends bacterial infections; it will be an ongoing arms race," Sontheimer said in the Tribune's article. "But if we can extend the useful life of antibiotics that are already out there, that will be one more arrow in our quiver in this fight against infectious disease."

Download Center

HTML - No Current Item Deck
  • Free Safety Management Software Demo

    IndustrySafe Safety Management Software helps organizations to improve safety by providing a comprehensive toolset of software modules to help businesses identify trouble spots; reduce claims, lost days, OSHA fines; and more.

  • Easy to Use Safety Incident App

    Record incidents on the go with IndustrySafe’s mobile app. Collect data for multiple types of incidents including including near misses, vehicle and environmental incidents, and employee and non-employee injuries; at job sites and remote locations—with or without web access.

  • Safety Training 101

    When it comes to safety training, no matter the industry, there are always questions regarding requirements and certifications. IndustrySafe is here to help. We put together a resource that’s easy to digest so you can get answers to your training questions and ensure you're complying with OSHA's standards.

  • Conduct EHS Inspections and Audits

    Record and manage your organization’s inspection data with IndustrySafe’s Inspections module. IndustrySafe’s pre-built forms and checklists may be used as is, or can be customized to better suit the needs of your organization.

  • Track Key Safety Performance Indicators

    IndustrySafe’s Dashboard Module allows organizations to easily track safety KPIs and metrics. Gain increased visibility into your business’ operations and safety data.

  • Industry Safe
comments powered by Disqus