Pre-pandemic Vaccine Promising Against Multiple Strains of H5N1

GlaxoSmithKline said today that new clinical trial data show for the first time that its pre-pandemic split antigen H5N1 vaccine "provides a substantial level of cross-immunity" against a drifted (diverse) strain of H5N1. The London-based health company said it hopes the immune response prompted by the vaccine could help prime an individual's immune system to rapidly respond against variants of the H5N1 strain, thus shielding the vaccinated population in an H5N1 human pandemic.

The data was presented in the first study at the IX International Symposium on Respiratory Viral Infections. GSK also said its proprietary adjuvant system means vaccine manufacturing capacity could be increased more than tenfold because only two doses of vaccine appeared to be effective. "The vaccine was shown to have an acceptable safety profile when compared to the control group. As expected, reactogenicity (injection site tenderness) was slightly higher in the vaccine group due to the use of the adjuvant system," it said in an online news release.

"I am extremely encouraged by the new trial data that has been reported today on GSK's candidate pre-pandemic influenza vaccine," said Jean Stéphenne, president of GlaxoSmithKline Biologicals, the vaccine division of GSK. "The data confirm that our pre-pandemic influenza vaccine has the ability to recognize and kill an H5N1 strain that is different to the one contained in the vaccine. This means that proactive administration of our pre-pandemic vaccine before or just after the start of the pandemic could help to substantially slow down the spread of disease." For more information, visit www.glaxosmithkline.com.

Download Center

HTML - No Current Item Deck
  • Free Safety Management Software Demo

    IndustrySafe Safety Management Software helps organizations to improve safety by providing a comprehensive toolset of software modules to help businesses identify trouble spots; reduce claims, lost days, OSHA fines; and more.

  • Easy to Use Safety Incident App

    Record incidents on the go with IndustrySafe’s mobile app. Collect data for multiple types of incidents including including near misses, vehicle and environmental incidents, and employee and non-employee injuries; at job sites and remote locations—with or without web access.

  • Complete Online Safety Training Courses

    Deliver state-of-the art, online safety training courses to your organization with IndustrySafe Training Management Software. Generate reports to track training compliance and automatically notify learners of upcoming or overdue classes.

  • Conduct EHS Inspections and Audits

    Record and manage your organization’s inspection data with IndustrySafe’s Inspections module. IndustrySafe’s pre-built forms and checklists may be used as is, or can be customized to better suit the needs of your organization.

  • Track Key Safety Performance Indicators

    IndustrySafe’s Dashboard Module allows organizations to easily track safety KPIs and metrics. Gain increased visibility into your business’ operations and safety data.

  • Industry Safe
comments powered by Disqus